Systemic autoinflammatory diseases are a new category of rheumatic and inflammatory conditions that differ from lupus and juvenile arthritis. SAIDs are inherited genetic conditions often involving fever syndromes. These are complex conditions that are difficult to diagnose because patients do not have blood markers, such as the autoantibodies used to identify certain diseases.

Symptoms of SAIDs include:

  • Recurrent fevers
  • Rash
  • Chest and abdominal pain
  • Blood tests often show systemic inflammation when no infections are present

Treatment uses medicines to control the inflammatory episodes.