The characteristics of this syndrome are a mixed venous-lymphatic malformation usually involving the extremities. There is usually a port wine like stain on the affected limb and there is usually a difference in size between the affected and nonaffected limb, the affected one being larger.
Its characteristics are a port-wine stain that involves the skin around the eye and cheek as well as the covering of the brain; seizures; atrophy of the brain tissue; and developmental delay. Early diagnosis is important to allow control of seizures and monitoring of eye pressures by an ophthalmologist to help preserve vision.
The Vascular Anomalies Center at Arkansas Children's is staffed by a closely integrated multidisciplinary team of physician specialists and related support staff representing the disciplines of Hematology/Oncology, Craniofacial Orthodontics, Pediatric Surgery, Research, Otolaryngology/Head and Neck Surgery, Pathology, Radiology, Dermatology, Pediatrics, and Orthopedic Surgery. Clinical team members work together to provide the needed care appropriate for each patient.
Approximately, ten percent of all children born in the United States are born with a vascular birthmark. While many of these birthmarks will disappear within a few years of age, about ten percent of these children have a birthmark that will require the opinion of a specialist. The parents of these children are often confused and feel helpless, due to their lack of knowledge regarding diagnosis and treatment options. Many recent advances have been made in the diagnosis and treatment of hemangiomas and vascular malformations. Our goal is to give you the most up-to-date information as well as give you resources to help you understand your child's condition. Each person with a vascular anomaly is different and not all treatment options will be appropriate for every patient. The information provided on vascular anomalies and treatment options is to be used as a general guideline.
The Vascular Anomalies Program provides treatments in a variety of ways. Some of these treatments include:
Research is an essential element of our Vascular Anomalies program, again utilizing the strength of the multidisciplinary team approach. Team members have made many significant advances in the field to continually advance treatment options and discover fundamental mechanisms of the underlying disease processes.
The Center for Investigation of Congenital Aberrancies in Vascular Development at the Arkansas Children's Research Institute was established in 2008. The center was created to open a dedicated molecular and biology laboratory to investigate vascular anomalies and conduct pilot work on in vitro and in vivo experimental models of disease. In the process, the laboratory has successfully isolated Hemangioma stem cells, explored various molecular markers, and grown various vascular anomalies in nude mice and tissue culture. Our team has presented this work at international scientific conferences and has several manuscripts in progress. Dr. Gresham Richter serves as the Research Director of the Center for Investigation of Congenital Aberrancies in Vascular Development. Our facility occupies 650 ft 2 that is fully operational to conduct the entire spectrum of laboratory techniques, including immunohistochemistry, Western blotting, Northern blotting, RTPCR, tissue culture, and animal experiments. Local institutional intramural funding has supported the initial equipment acquisition and pilot projects.
Some of the awards our research team has won are as follows:
William P. Potsic Basic Science Award for Outstanding Achievement in the Field of Pediatric Otolaryngology from the American Society of Pediatric Otolaryngology
Their achievement is the first time in the award program's history that researchers from the same institute were awarded first and second places in the same year.
The organizations and support groups provided may be helpful to families and patients of the Vascular Anomalies Clinic.
Manage your child's medical information and connect with your Arkansas Children's medical team anytime online!Log in to MyChart